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Creative Biolabs
City:
New York
Industry:
Pharmaceuticals
Country/Region:
United States United States
Business Type:
Professional
 

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Knobs-Into-Holes

Knobs-Into-Holes

Product Name Knobs-Into-Holes
Company Creative Biolabs
Short description Knobs-Into-Holes
Detail Scientists from Creative Biolabs introduced knobs-into-holes amino acid changes to perform rational design in antibody engineering. The principle is that heavy chains (H) of human immunoglobulin IgG interact at the level of their CH3 domains directly, whereas, at the level of their CH2 domains, they interact via the carbohydrate attached to the Asn N84.4 in the DE turn. https://www.creative-biolabs.com/KNODBS-INTO-HOLE.html
Title Knobs-Into-Holes
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Condition New
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