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Creative Biolabs
City:
New York
Industry:
Pharmaceuticals
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United States United States
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Professional
 

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QUADROMA CELL LINES

QUADROMA CELL LINES

Product Name QUADROMA CELL LINES
Company Creative Biolabs
Short description QUADROMA CELL LINES
Detail "The first tri-functional antibody successfully produced from quadromas is catumaxomab. At first, mouse hybridoma cells whose monoclonal antibodies target one of the desired antigens are produced. Independently, rat hybridoma cells targeting the other antigen are produced. Then, these two cell types are hybridised, yielding hybrid-hybridomas or quadromas, which produce hybrid (tri-functional) antibody as well as pure mouse and pure rat antibody. The tri-functional antibody is extracted chromatographically with protein A. The disadvantage of quadromas is the produced antibodies are a mixture. Especially if these two hybridoma cells are the same species, up to ten different kinds of antibody can be produced, most of which have mismatched heavy or light chains, or both. Figure 2 below presents the possible combinations of light and heavy chains in antibodies produced by quadroma cell lines.More information, please visit the website: http://www.creative-biolabs.com/QUADROMA-CELL-LINES.html"
Title Health&Medical-Biological Products
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